IT is now generally accepted that celiac disease in children and idiopathic steatorrhea (nontropical sprue) in adults are phases of the same disease. 1 For convenience we refer to this entity as ...

Sept. 27, 2002 — A report in the Sept. 27 issue of Science identifies the culprit inducing celiac sprue as a 33-mer peptide of gluten, and a bacterial prolyl endopeptidase which can metabolize this ...

Celiac sprue (CS) is a gluten-sensitive enteropathy with many autoimmune features. CS involves multiple organs through immune and nonimmune processes, and is frequently associated with other ...

OVER a period of seven years, my colleagues and I have treated 29 patients with nontropical sprue by eliminating gluten from their diets. The average age of this series of 26 women and 3 men was forty ...

Seven years ago, during an endoscopy for what was thought to be acid reflux, the doctor looked at the screen and exclaimed "Oh! Celiac sprue!" "I'm awake. I'm not sedated or anything," continued the ...

Mrs. Burrows was worried about her granddaughter. “She hadn’t been well for about a year. We always knew she had a sensitive stomach, but then she started having diarrhea and nausea every day,” she ...

Celiac Sprue is an autoimmune disease of the small intestine induced by exposure to dietary gluten, but the molecular trigger for gluten toxicity remains unclear. In September 27 Science, Lu Shan and ...

Researchers have found a peptide molecule that triggers celiac sprue – a severe inflammation of the intestine that results from eating wheat and related grains – and propose a treatment strategy that ...

Scientists have discovered what may be a successful non-dietary therapy for celiac sprue, an inherited inflammatory disorder of the small intestine that impacts an estimated 1 in 200 people around the ...

Celiac disease — also known as celiac sprue or gluten intolerance — is a genetic disease that results in the inability to properly digest gluten, a type of protein found in wheat, barley and rye. When ...

Dear Dr. Roach: I had a duodenum biopsy to rule out sprue. The biopsy results were that my duodenal mucosa showed: “… mucosal inflammation with marked flattening of the mucosa. Micro­scopic ...