To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...
The body has to clear away dead cells and other unnecessary or unneeded stuff, and one mechanism that is crucial to the degradation of such materials is called LC3-associated phagocytosis (LAP). This ...
2don MSN
Catching a scramblase in the act could pave the way to improved blood disorder and cancer treatments
Weill Cornell Medicine investigators have revealed the detailed workings of a cell membrane protein that has essential roles ...
Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment ...
Lipid research investigates the structure, function and metabolism of fats, covering their roles in industrial processes, the environment and health. Emerging research areas include nutrient ...
Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body's ...
Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...
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