The immune system relies on a fine-tuned balance between the generation of peptide antigens and their presentation to cytotoxic T cells via Major Histocompatibility Complex (MHC) class I molecules.

Researchers at University of Tsukuba have found that the phosphate concentration in proximal tubule fluid, estimated from urine and blood tests, is associated with elevated renal tubular damage ...

Interferon signaling and outcomes in triple-negative breast cancer (TNBC) in FinXX, CALGB 40603 (Alliance) and real-world clinico-genomic data.

In this study, patients with multiple sclerosis (MS) and the experimental autoimmune encephalomyelitis (EAE) mouse model of MS exhibited an accumulation of Th17 cells in the small intestine.