The American Journal of Managed Care

Allogeneic vs Autologous CAR T-Cell Therapy Explained

On February 13, Allogene Therapeutics published new long-term follow-up data on cemacabtagene ansegedleucel, showing the investigative allogeneic chimeric antigen receptor (CAR) T-cell therapy ...
Everyday Health

What to Expect When Starting CAR T-Cell Therapy for Large B-Cell Lymphoma

I f your doctor has recommended chimeric antigen receptor (CAR) T-cell immunotherapy for large B-cell lymphoma (LBCL), you’ve likely already tried several standard treatments, and the cancer did not ...
The Conversation

CAR‑T cell therapy is revolutionising cancer treatment – here’s how it works

Personalised medicine is already a reality in clinical practice, and CAR-T cell therapy is one of its most promising tools. This innovative approach, which involves genetically modifying the cells of ...
Medscape

New Syndrome With CAR T-Cell Therapy in Autoimmune Diseases

A substantial proportion of patients with autoimmune diseases experienced a new side effect called local immune effector cell–associated toxicity syndromes (LICATS) after receiving chimeric antigen ...
Johns Hopkins Medicine

Single Nutrient Fuels Cancer-Fighting Power of T Cells

Using a variety of laboratory and animal models, the team found that cysteine fuels the production of the antioxidant ...

Transcription factors form continuous 'circuit' that regulates T-cell exhaustion

Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion ...